Problem in ajaxToolkit:AjaxFileUpload when use url rewrite

hello to all

i use ajaxToolkit:AjaxFileUpload and url rewrite in global.asax 

        protected void Application_Start(object sender, EventArgs e)
        {
            RegisterRoutes(RouteTable.Routes);
        }


        public static void RegisterRoutes(RouteCollection routes)
        {
            routes.MapPageRoute("","services/{action}/","~/services/service.aspx");
        }

when i upload i file i get this error

Uncaught Failed to starting upload.

Failed to load resource: the server responded with a status of 404 (Not Found)

but when i remove global.asax in project file upload is work correctly

please help me