When I run my project on asp.net 4.0 seem it's ok but when I begun to clicking the textbox and linkbutton the error pop-up

solution done so far;
-edit iexplorer.exe to registry make sure the value is 1;
- modify the security setting on IE9 especially on activex plug-in
but still not working...
when I click yes the error code point to this code
if(window.self.location.protocol.indexOf('http')>-1 && window.self==window.top)help thanks